Usually, the patients suffering from simple endometrial hyperplasia are accompanied with pelvic inflammatory disease, pelvic dropsy or cervicitis, and are affiliated with excessive vaginal fluid and yellow vaginal fluid. By which, it indicates the connection between endometrial hyperplasia and inflammatory stimulation. Accordingly, Fuyan Pill can clear away heat and toxic material and then produce a positive effect against endometrial hyperplasia. Fuyan Pill focuses on detoxifying and sterilizing, and couples with the function of strengthening spleen and promoting urination, to achieve the objective of eliminating the pathological changes of endometrial bodiness.

The endometrium refers to the mucosa covering the uterine cavity which grows from the period of childhood. In each menstrual cycle, it generates periodical changes accordingly, that is, exfoliating from uterine cavity. Thus forms menses. If the egg released by the uterus is not fertilized this time, the menses will go on next time. For the cycle time of menses is adjusted by ovarian hormone, the disorder of it will cause menstrual disorder. Thus, the endometrium will change accordingly, manifesting as thickening of endometrium. In the duration of menstruation, the functional layer of endometrium will exfoliate while the basal lamina retains. Reaching the proliferative stage, namely, the 6th to 14th of menstruation, the endometrium will reach up to 1.0 to 3.0 mm, and the secretory phase(15th to 28th of menstruation), 5 to 7 mm, whereas the normal thickness of endometrium is among 0.2 to 1.0 cm.

Endometrial bodiness is usually manifested as menostasis or dysfunctional uterine bleeding and the later is especially common. Endometrial bodiness could emerge in the crowds of different age groups, including adolescent age, reproductive period, peri-menopausal period and post-menopausal period.

Clinically, endometrial bodiness should be attributed to inflammatory stimulation primarily. It is usually manifested as abnormal uterine bleeding irregularly and excessively. The patients, after a long time of menostasis, might emerge continuous bleeding which might last for one month or even induce hemorrhagic shock in the case of profuse bleeding, or shortening of cycle and prolonging of menstrual period.

Endometrial bodiness includes simple hyperplasia, complex hyperplasia, thickening of glandular organ and atypical cellular proliferation. Especially in the last two cases, it would cause cancer with a high probability and should be treated seriously.
Usually, the pathological features of endometrial hyperplasia are manifested as: the universally thickening of endometrium that might reach up to 0.5 to 1 cm; smoothing and softening of endometrial surface; overgrowth of endometrial glandular organ and interstitial substance both, in which the glandular organs are increasing obviously, being of different shapes and sizes and of uneven distribution; occasionally emerging expansion and encapsulation of glandular organs, and column-shaped of epithelial cells with a deficiency of secretion and in most cases a pseudostratified structure; mitotic figure of nucleolus which might be seen commonly; and packing closely of interstitial cells.

Characteristically, simple endometrial hyperplasia appears that the uterus in the case of emerging pathologic change is comparatively large than in normal case, that the endomembrane is thickening obviously and sometimes presents in the shape of diffused polypus, and that the amount of materials produced by curettage, which might be mixed with red, smooth and polypoid tissue, is large.
Microscopically, it presents diffuse lesion, which might involve the functional layer and basal lamina. Due to the overgrowth of endometrial glandular organ and interstitial substance at the same time, the outline of endometrium is comparatively flat. The shape of epithelial cells in this case is similar as in the case of advanced proliferative stage, being non-heterologous.