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What are the Warning Sign of the Canceration of Adenomyosis?

In recent years, the incidence of adenomyosis has shown a significant upward trend. This is related to the increase in the rate of cesarean section, artificial abortion, and hysteroscopic laparoscopic operations. The incidence is about 20%-90% in patients with chronic pelvic pain and dysmenorrhea.

Adenomyosis is rarely cancerous and rarely malignant. But adenomyosis can cause many uncomfortable symptoms in women. First, adenomyosis can cause dysmenorrhea symptoms that appear progressively worse. Second, adenomyosis can cause the uterus to enlarge significantly, resulting in a feeling of bulging in the lower abdomen. Finally, adenomyosis can lead to significantly increased menstrual flow with blood clots, incessant menstruation, and prolonged periods, which can lead to blood loss anemia and infection.
Although the cancer rate of adenomyosis is only about 1%, there are still very unfortunate patients in that 1%. Therefore, it is necessary to pay attention to the changes of diseases in daily life.
Today let's learn about 4 types of warning symptoms.
1. The Uterus Suddenly and Rapidly Enlarges
If the uterus grows slowly during the treatment of adenomyosis patients, the possibility of malignant transformation is very low. If you suddenly find that the uterus is enlarged, you should be careful at this time and go to the hospital for a detailed examination as soon as possible. Therefore, it is recommended that patients get regular examinations to check the size of the uterus.
2. Dysmenorrhea Suddenly Increases, Relieves or Disappears
Patients with adenomyosis with dysmenorrhea should not be careless if dysmenorrhea suddenly increases, relieves or disappears. Especially for patients whose symptoms of dysmenorrhea were not very serious in the past, when recent dysmenorrhea is much more severe than before, it may be cancerous. While for patients whose dysmenorrhea was very serious before, when the dysmenorrhea suddenly relieved or disappeared without any incentive, it’s not a good time to rejoice; instead, it was necessary to check and diagnose in time to see if the adenomyosis was cancerous.
3. Menstrual Period Lasts Longer with Endless Vaginal Bleeding
After the occurrence of cancer, the patient will experience prolonged menstruation and incessant vaginal bleeding. It is worth noting that the symptoms of increased menstrual flow in patients with adenomyosis generally only exist during the menstrual period. The bleeding stops right after the menstrual period. But if it is cancerous, the bleeding doesn’t stop, with a small amount but long-lasting time, and will even last for 15 days, 20 days or even a whole month. While one period has not completely ended yet, the next period begins.
When encountering adenomyosis patients with this symptom in clinic, especially those over 40 years old with long-lasting periods for 20 days in last half year, the doctor will recommend them to do a curettage first, that is, diagnostic curettage. Doctors scrape out a little of the endometrium and send it to a pathological test to see whether there are symptoms of atypical hyperplasia or precancerous lesions.
4. CA125 suddenly increases significantly
Patients with adenomyosis should pay attention to the routine examination. If the CA125, in the range of tens or below 200 in the previous examination, suddenly rises to hundreds or even thousands recently, further examinations must be done in time. 
In conclusion, prompt examinations are needed when the uterus suddenly and rapidly enlarges; dysmenorrhea suddenly increases, relieves or disappears; menstrual period lasts longer with endless vaginal bleeding; CA125 suddenly increases significantly.
Of course, about 35% of patients will have no obvious symptoms.
In fact, instead of worrying about whether adenomyosis will become cancerous, it is better to treat it as soon as possible. For example, you can take Fuyan Pill, a herbal medicine. Traditional Chinese medicine doctors believe that adenomyosis is caused by cold condensation, Qi stagnation, heat burning and other factors leading to stagnation of blood and uterus. This disease belongs to the category of "dysmenorrhea" and "infertility" in traditional Chinese medicine. Therefore, TCM follows the principles of promoting blood circulation and removing blood stasis and clearing away heat and dampness.
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