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Why Do You Miscarry More Often? Endometriosis May Be the Answer
Endometriosis refers to the growth function of the endometrium, which appears in other parts of the body outside the endometrial covering mucosa, with dysmenorrhea, irregular menstruation, infertility, sexual intercourse pain as the main clinical manifestations.
It is a common disease in women of childbearing age. The incidence of a spontaneous abortion caused by it is higher in the clinic, with an average of 40%, which is higher than that of normal pregnancy. So why does endometriosis lead to abortions?
The etiology of endometriosis is unknown, which is usually considered to be related to immune and endocrine disorders. In addition to infertility, it may also lead to poor egg quality, poor embryonic development, poor endometrial receptivity, and so on, which may lead to embryo development block and spontaneous abortion.
1. Oxidative stress and Immunology
The level of oxidative stress increased in endometriosis, such as the increase of 8-hydroxydeoxyguanosine (a marker of DNA damage caused by oxidative stress) concentration and the increase of the proportion of embryos with abnormal morphology.
At present, some scholars think that endometriosis is an immune disease; many kinds of cytokines are abnormal, such as tumor necrosis factor α, IL-6, IL-8, and so on. The increase in these cytokines will lead to the decline of egg and embryo quality. These factors will lead to the occurrence of spontaneous abortion.

2. Progesterone resistance
The mechanism of progesterone resistance caused by endometriosis is unknown, which may be related to the abnormal expression of the progesterone receptors. In addition, the abnormal expression of many steroid synthetases in granulosa cells leads to a decrease of progesterone synthesis, which is also the cause of spontaneous abortion.
3. Prostaglandin factors
Because of the increase of prostaglandin synthesis and slow decomposition and excretion in ectopic endometrium, prostaglandins are accumulated locally, and the increase of prostaglandins can also cause uterine contraction, leading to the occurrence of abortions.
4. High incidence of endometrial polyps and low endometrial receptivity
The high incidence of polyps in endometriosis women affects the implantation of embryos. The endometrial receptivity, embryo implantation, pregnancy rate decreased, and the spontaneous abortion rate of endometriosis increased.
Endometriosis is the most common chronic disease in gynecology. The recurrence rate is 40-50%, even higher than that of cancer. It can not be completely cured by a certain treatment and needs long-term comprehensive management and treatment.
Because endometriosis is a hormone-dependent disease, it is mainly treated with the hormone. When the hormone treatment is ineffective, or the condition is serious, surgery is used. Although these methods have a certain therapeutic effect, the recurrence rate is high, side effects are large, and the long-term effect is not satisfactory.
At this time, herbal medicine Fuyan Pill invented by Dr. Lee Xiaoping, can be used for treatment. It is not only non-toxic and side-effects, but also anti-inflammatory and bactericidal. It can clear the pathogenic mechanism of patients, eliminate the inflammatory lesions in uterus, pelvis, ovary, etc., and reduce the probability of endometriosis.
Moreover, it can promote blood circulation and remove blood stasis, improve women's body functions, and keep a balance between their Qi and blood, so as to achieve the effect of regulating menstruation.
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