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Environmental Factors May Also Lead to Endometriosis

Endometriosis(EMS) is an estrogen-dependent disease, and estrogen may be one of the factors regulating the expression of these chemokines and their receptors. In addition, environmental factors may also increase the incidence rate of endometriosis. It is found that dioxin can increase the risk of endometriosis in women.
Dioxin is a kind of environmental pollutant which seriously affects human health. It has the characteristics of pox, teratogenesis, immunotoxicity, reproductive toxicity, and endocrine toxicity. Dioxins are by-products produced in the production process, such as paper bleaching, polyethylene plastic production, pesticide Mucun preservative, dry cleaning agent, herbicide production, industrial accidents and metal recovery, exhaust gas from automobile exhaust, especially incineration waste and medical waste.
The ways of dioxin entering the human body are as follows:
1. Absorbed through the digestive tract, which is the main way of human poisoning;
2. Absorbed through the respiratory tract;
3. Absorbed through the skin.
In 1993, Rier and other reports reported the direct relationship between dioxin and the incidence of endometriosis. They found that the incidence rate of endometriosis in Ganges RIver monkeys with chronic dioxin exposure was significantly higher than that of the control group in 4 years, and the severity of disease was positively correlated with exposure dose.

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